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A 22-year-old male presented with a 2-week history of generalised malaise, weight loss and bruised skin without any trauma. He recently developed 5 days of productive cough and fevers. He was admitted to hospital for further investigations but had a sudden loss of consciousness and died a few minutes after admission to hospital.
The specimen is a horizontal slice of brain displaying the superior cut surface. In the right frontal and parietal regions are two large intraparenchymal haemorrhages each 5 cm in maximum diameter. Several smaller haemorrhages are present in the white matter of both hemispheres. This is an example of multiple intraparenchymal cerebral haemorrhages in a patient with acute myeloid leukaemia (AML).of vascular lumen and involvement of the blood vessel walls. The inflammation extended into the cerebral parenchyma causing haemorrhage and necrosis.
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