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Further Information
Primary lymphoma of the thyroid is rare but should always be considered as a differential diagnosis of any thyroid mass or nodule. Primary thyroid lymphomas are rare, and are usually of the non-Hodgkin type. Lymphoblastic lymphoma is an aggressive form of non-Hodgkin’s lymphoma (NHL), usually seen in children. Currently, the only known risk factor for developing primary thyroid lymphoma is chronic autoimmune (Hashimoto’s) thyroiditis, with a 50% occurrence rate. Thyroid lymphoma should be considered in any individual presenting with a rapidly enlarging ‘goitre’, as over 90% of individuals with this disease present this way. As the goitre enlarges, there can be compression of nearby structures such as the trachea, oesophagus and neck vessels (the common carotid in this case). The resulting symptoms include stridor or hoarseness, dysphagia and neck pain. Other systemic symptoms of lymphoma include so-called B-symptoms, i.e. night sweats, fevers and loss of weight. Diagnosis can be achieved by an ultrasound scan followed by fine needle aspiration or excisional biopsy. As thyroid lymphomas cannot be excluded from Hashimoto’s or other carcinoma, cytology and immunohistochemical stain of the biopsied tissue is required to confirm the diagnosis.
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